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Improvent (100mcg+20mcg)/Puff
Improvent MDI is indicated for the management of chronic obstructive pulmonary disease (COPD) in patients who remain symptomatic on a single bronchodilator. It provides dual bronchodilation by combining beta-agonist and anticholinergic agents to relieve bronchospasm.
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✅ Description:
Improvent combines two distinct bronchodilators:
- Salbutamol, a short-acting β₂-adrenergic agonist, relaxes airway smooth muscles.
- Ipratropium Bromide, an anticholinergic, blocks acetylcholine at muscarinic receptors, reducing bronchial constriction.
Together, they deliver enhanced bronchodilation via complementary mechanisms. The inhaler uses an eco-friendly HFA propellant, avoiding ozone-depleting CFCs.
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✔️ Uses of Improvent
- Chronic obstructive pulmonary disease (COPD)
✔️ Dosage & Administration of Improvent
Adults (including the elderly):
2 puffs up to 4 times daily. Additional puffs may be taken as needed, but not exceeding 12 puffs in 24 hours.
Proper inhaler technique is essential for optimal drug delivery. Always shake the canister before use. Inhale slowly and deeply while pressing the canister, and hold your breath for 10 seconds.
Cleaning:
Clean the mouthpiece at least weekly. Remove the canister before rinsing the plastic actuator in warm water. Dry thoroughly before reuse.
✔️ Side Effects: Improvent
Due to Salbutamol: Tremors, headache, rarely muscle cramps, bronchospasm, or hypersensitivity.
Due to Ipratropium: Headache, cough, dry mouth, nausea, chest discomfort, or sinusitis (infrequent).
✔️ Caution is advised when used alongside:
Other anticholinergics or sympathomimetics
MAO inhibitors, tricyclic antidepressants, or non-potassium-sparing diuretics
May enhance cardiovascular side effects.
✔️ Contraindications
Known hypersensitivity to soya lecithin, peanut, or soybean
Allergic to atropine or other formulation components
✔️ Use in Pregnancy & Lactation
Salbutamol (Pregnancy Category C): Use only if potential benefits justify risks.
Ipratropium (Category B): No known teratogenicity.
Caution is advised during lactation due to unknown excretion in breast milk.
✔️ Use with care in patients with:
Glaucoma, prostatic hyperplasia, or urinary retention
Conditions like seizures, hyperthyroidism, diabetes, or those hypersensitive to adrenergics
✔️ Storage
Store in a cool, dry place, away from heat or sunlight. Do not puncture or incinerate the canister. Keep out of reach of children and avoid contact with the eyes.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
